May 18, 2021

Essential Biochemistry pdf 4th edition free download

Essential Biochemistry pdf, 4th Edition is comprised of biology, pre-med, and allied health topics and presents a broad, but not overwhelming, base of biochemical coverage that focuses on the chemistry behind biology. Furthermore, it relates the chemical concepts that scaffold the biology of biochemistry, providing practical knowledge also as many problem-solving opportunities to hone skills. Key Concepts and Concept Review features help students spot and review important takeaways in each section.

New to this edition

Many details in the text and illustration program have been updated, with virtually no section left untouched. Some signify can’t changes are worth mentioning: Chapter 3 includes an updated discussion of genomics and a completely new presentation of DNA sequencing technologies and the use of CRISPR-Cas to edit genes. Other new items include a discussion of archaeal lipids, details on the GLUT membrane transport protein, a box on exosomes, new illustrations of respiratory cilia and bacterial peptidoglycan, new molecular graphics of mitochondrial respiratory complexes, an updated presentation of the ribonucleotide reductase mechanism, and more information on the microbiome, cancer, and obesity.

Descriptions of DNA replication and transcription have been extensively modifying, with numerous new diagrams to present a more realistic picture of these processes. The histone code and readers, writers, and erasers are explained. New details on RNA splicing and protein translocation round out the revised text. Eight health-related topics that were previously configured need to short boxes have been updated and expanded to Clinical Connection sections to give them the appropriate attention: 2.5 Acid-Base Balance in Humans, 4.5 Protein Misfolding and Disease, 5.2 Hemoglobin Variants, 6.5 Blood Coagulation, 7.4 Drug Development, 13.5 Disorders of Carbohydrate Metabolism, 19.4 Cancer Metabolism, and 20.4 Cancer as a Genetic Disease.

With the same goal of making it easy for students to navigate complex topics, some material within sections has been reorganized, and several new sections of text now focus on key content areas: 14.3 Thermodynamics of the Citric Acid Cycle, 17.1 Lipid Transport, 18.5 Nucleotide Metabolism, 20.5 DNA Packaging, 21.1 Initiating Transcription, and 22.1 t-RNA and the Genetic Code. Above all, the focus of the fourth edition is the ease of use, particularly for students and instructors taking advantage of new ways to assess student understanding. New Learning Objectives at the start of every section are based on verbs, giving students an indication of what they need to be able to do, not just know. Before You Go On study hints at end of each section reinforce the activities that support learning. The end-of-chapter problem sets have been refreshed, with a total of 1,624 problems (averaging 74 per chapter, an increase of 18% over the previous edition). Problems are grouped by section and offered in pairs, with the answers to odd-numbered problems provided in an appendix.

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Preface of Essential Biochemistry pdf

Several years ago, we set out to write a short biochemistry textbook that combined succinct, clear chapters with extensive problem sets. We believed that students would benefit from a modern approach involving broad but not overwhelming coverage of biochemical facts, focusing on the chemistry behind biology, and providing students with practical knowledge and problem-solving opportunities. Our experience in the classroom continues to remind us that effective learning also requires students to become as fully engaged with the material as possible. To that end, we have embraced a strategy of posing questions and suggesting study activities throughout each chapter, so that students will not simply read and memorize but will explore and discover on their own—a truer reflection of how biochemists approach their work in the laboratory or clinic. As always, we view our textbook as a guidebook for students, providing a solid foundation in biochemistry, presenting complete, up-to-date information, and showing the practical aspects of biochemistry as it applies to human health, nutrition, and disease. We hope that students will develop a sense of familiarity and comfort as they encounter new material, explore it, and test their understanding through problem-solving.

Table of contents of Essential Biochemistry pdf

Part 1


1 The Chemical Basis of Life

2 Aqueous Chemistry

Part 2

Molecular Structure and Function

3 From Genes to Proteins

4 Protein Structure

5 Protein Function

6 How Enzymes Work

7 Enzyme Kinetics and Inhibition

8 Lipids and Membranes

9 Membrane Transport

10 Signaling

11 Carbohydrates

Part 3


12 Metabolism and Bioenergetics

13 Glucose Metabolism

14 The Citric Acid Cycle

15 Oxidative Phosphorylation

16 Photosynthesis

17 Lipid Metabolism

18 Nitrogen Metabolism

19 Regulation of Mammalian Fuel Metabolism

Part 4

Genetic Information

20 DNA Replication and Repair

21 Transcription and RNA

22 Protein Synthesis


CHARLOTTE PRATT received a B.S. in biology from the University of Notre Dame and a Ph.D. in biochemistry from Duke University. She is a protein chemist who has conducted research in blood coagulation and inflammation at the University of North Carolina at Chapel Hill. She is currently Associate Professor in the Biology Department at Seattle Pacific University. Her interests include molecular evolution, enzyme action, and the relationship between metabolic processes and disease. She has written numerous research and review articles, has worked as a textbook editor, and is a co-author, with Donald Voet and Judith G. Voet, of Fundamentals of Biochemistry, published by John Wiley & Sons, Inc.

KATHLEEN CORNELY holds a B.S. in chemistry from Bowling Green (Ohio) State University, an M.S. in biochemistry from Indiana University, and a Ph.D. in nutritional biochemistry from Cornell University. She currently serves as a Professor in the Department of Chemistry and Biochemistry at Providence College where she has focused on expanding the use of case studies and guided inquiry across a broad spectrum of classes. Her interest in active pedagogy has led to her involvement in national programs including Project Kaleidoscope, the POGIL Project, and the Howard Hughes Medical Institute SEA PHAGES program, which has also fueled her current experimental research in phage genomics. She has been a member of the editorial board of Biochemistry and Molecular Biology Education and has served for several years as coordinator of the undergraduate poster competition at the annual meeting of the American Society for Biochemistry and Molecular Biology.

Product details

  • Publisher: Wiley; 4th edition (August 22, 2017)
  • Language: English
  • Ring-bound: 720 pages
  • ISBN-10: 1119444373
  • ISBN-13: 978-1119444374
  • Item Weight: 2.8 pounds
  • Dimensions: 8.4 x 1.2 x 11 inches
  • Best Sellers Rank: #833,404 in Books
    • #704 in Biochemistry (Books)
    • #3,159 in Biology & Life Sciences (Books)
  • Amazon Price:
    • Hard Cover: 47.43$
    • Ring-Bound: 129.75$
  • Buy from Amazon: buy-on-amazon

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